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Image Search Results
Journal: Proteomics. Clinical Applications
Article Title: Proteomic analysis identified potential age‐associated prognostic biomarkers in pneumonia‐derived paediatric sepsis
doi: 10.1002/prca.202100036
Figure Lengend Snippet: Correlation analysis between biomarkers and sepsis outcome in infants and toddlers. (A) Determination of HP, THBS1, and SAA concentrations by ELISA. (B) ROC curve analysis of infant‐specific prognostic biomarkers of sepsis: HP and THBS1. * indicates a significant difference among the patient groups with p <0.05; ns indicates a difference between the patient groups without statistical significance, p >0.05. THBS1 was evaluated with 1/THBS1 in the ROC curve analysis
Article Snippet: The concentrations of haptoglobin (HP), Thrombospondin 1 (THBS1) and SAA1/2 in patient plasma were analysed in 45 randomly chosen sepsis plasma samples from the cohort of this study using the
Techniques: Enzyme-linked Immunosorbent Assay
Journal: Laboratory Investigation; a Journal of Technical Methods and Pathology
Article Title: Hemoglobin oxidation generates globin-derived peptides in atherosclerotic lesions and intraventricular hemorrhage of the brain, provoking endothelial dysfunction
doi: 10.1038/s41374-020-0403-x
Figure Lengend Snippet: Healthy (CTR), atheromatous lesion (Ath), and complicated lesion (Comp) human carotid artery samples were subjected to SDS-PAGE and stained with Coomassie Brilliant Blue R-250 ( n = 3) ( a ). Cerebrospinal fluid: healthy (CTR), early-phase intraventricular hemorrhage (EIVH), and late-phase intraventricular hemorrhage (LIVH) samples were subjected to SDS-PAGE and stained with Coomassie Brilliant Blue R-250 ( b ). After the oxidation of hemoglobin with hydrogen peroxide (FHb), the sample was subjected to SDS-PAGE and stained with Coomassie Brilliant Blue R-250 ( c ). Hemoglobin (1), haptoglobin (2), FHb (3), and hemoglobin incubated with haptoglobin and hydrogen peroxide (4) were subjected to SDS-PAGE and stained with Coomassie Brilliant Blue R-250 ( d ). Structure of hemoglobin according to the 3onz.pdb crystal structure deposited in the Protein Data Bank ( e ); the sequences of the peptides whose biological effects were examined are indicated, and the arrows show their position in the 3D structure of hemoglobin. Blue indicates chain A, red indicates chain B, and green indicates the peptides.
Article Snippet:
Techniques: SDS Page, Staining, Incubation